New sesquiterpene quinols from a Micronesian sponge, Aka sp.

Venugopal J.R.V. Mukku; Ru A. Edrada; Francis J. Schmitz; Michelle Kelly Shanks; Babathosh Chaudhuri; Doriano Fabbro

doi:10.1021/np0205506

New sesquiterpene quinols from a Micronesian sponge, Aka sp.

Venugopal J.R.V. Mukku
, Ru A. Edrada
, Francis J. Schmitz
, Michelle Kelly Shanks
, Babathosh Chaudhuri
, Doriano Fabbro

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

Original language	English (US)
Pages (from-to)	686-689
Number of pages	4
Journal	Journal of Natural Products
Volume	66
Issue number	5
DOIs	https://doi.org/10.1021/np0205506
State	Published - May 1 2003
Externally published	Yes

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10.1021/np0205506

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title = "New sesquiterpene quinols from a Micronesian sponge, Aka sp.",

abstract = "Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.",

author = "Mukku, \{Venugopal J.R.V.\} and Edrada, \{Ru A.\} and Schmitz, \{Francis J.\} and Shanks, \{Michelle Kelly\} and Babathosh Chaudhuri and Doriano Fabbro",

year = "2003",

month = may,

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doi = "10.1021/np0205506",

language = "English (US)",

volume = "66",

pages = "686--689",

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AU - Mukku, Venugopal J.R.V.

AU - Edrada, Ru A.

AU - Schmitz, Francis J.

AU - Shanks, Michelle Kelly

AU - Chaudhuri, Babathosh

AU - Fabbro, Doriano

PY - 2003/5/1

Y1 - 2003/5/1

N2 - Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

AB - Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

UR - https://www.scopus.com/pages/publications/0038527304

UR - https://www.scopus.com/pages/publications/0038527304#tab=citedBy

U2 - 10.1021/np0205506

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EP - 689

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 5

ER -

New sesquiterpene quinols from a Micronesian sponge, Aka sp.

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