TY - JOUR
T1 - New sesquiterpene quinols from a Micronesian sponge, Aka sp.
AU - Mukku, Venugopal J.R.V.
AU - Edrada, Ru A.
AU - Schmitz, Francis J.
AU - Shanks, Michelle Kelly
AU - Chaudhuri, Babathosh
AU - Fabbro, Doriano
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.
AB - Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.
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U2 - 10.1021/np0205506
DO - 10.1021/np0205506
M3 - Article
C2 - 12762808
AN - SCOPUS:0038527304
SN - 0163-3864
VL - 66
SP - 686
EP - 689
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 5
ER -
