New sesquiterpene quinols from a Micronesian sponge, Aka sp.

Venugopal J.R.V. Mukku, Ru A. Edrada, Francis J. Schmitz, Michelle Kelly Shanks, Babathosh Chaudhuri, Doriano Fabbro

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

Original languageEnglish (US)
Pages (from-to)686-689
Number of pages4
JournalJournal of Natural Products
Issue number5
StatePublished - May 1 2003
Externally publishedYes


Dive into the research topics of 'New sesquiterpene quinols from a Micronesian sponge, Aka sp.'. Together they form a unique fingerprint.

Cite this