New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

  • Cheng Zhu Wu
  • , An Na Moon
  • , Jae Hyuk Jang
  • , Dongho Lee
  • , Sun Young Kang
  • , Joon Tae Park
  • , Jong Seog Ahn
  • , Bang Yeon Hwang
  • , Young Ho Kim
  • , Hong Sub Lee
  • , Young Soo Hong

Research output: Contribution to journalComment/debatepeer-review

12 Scopus citations
Original languageEnglish (US)
Pages (from-to)461-463
Number of pages3
JournalJournal of Antibiotics
Volume64
Issue number6
DOIs
StatePublished - Jun 2011
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported in part by the 21C Frontier Microbial Genomics and Application Center and Global R&D Center program, the Ministry of Science and Technology, Republic of Korea and by a grant from KRIBB Research Initiative Program. We thank the Korea Basic Science Institute for the NMR measurements

Keywords

  • Hsp90 inhibitor
  • biosynthetic engineering
  • geldanamycin
  • non-quinone geldanamycin

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