New diarylheptanoids and a hydroxylated ottelione from Ottelia alismoides

Thomas R. Hoye, Seif Eldin N Ayyad, Hollie J. Beckord, Susan G. Brown

Research output: Contribution to journalArticlepeer-review

Abstract

Ten new diarylheptanoids (2, 3, 4, 5a-d, 6, 7, and 8) have been isolated from an extract of Ottelia alismoides. The structures of these previously unknown metabolites were determined by NMR spectroscopic analysis. A previously unknown, hydroxylated analog of the known otteliones A and B (1a and 1b)-namely, 3a-hydroxyottelione (13)-was also isolated. The 1H NMR analysis of the Mosher esters of alcohols derived from otteliones A and B (S-17/R-17 and S-20/R-20) are also reported.

Original languageEnglish (US)
Pages (from-to)351-358
Number of pages8
JournalNatural Product Communications
Volume8
Issue number3
DOIs
StatePublished - Mar 2013

Keywords

  • Diarylheptanoids
  • Ottelia alismoides.
  • Otteliones

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