Abstract
Judicious control of ligand steric bulk and auxiliary structural elements enables the construction of novel synthetic complexes that model the properties of metalloprotein active sites, thus providing insight into their structure and function. Major recent developments include the synthesis of a number of unusual and biologically relevant complexes of copper and iron using elaborate N-donor and O-donor ligands.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 188-195 |
| Number of pages | 8 |
| Journal | Current opinion in chemical biology |
| Volume | 5 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2001 |
Bibliographical note
Funding Information:Research described in the references from our laboratory has been supported by the National Institutes of Health (GM47365).
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