The author reports on a 67 yr old male patient with the NBCC syndrome who, along with the usual changes, has numerous keratinizing cutaneous cysts and the previously unrecognized occurrence of colonic polyps. This constellation of abnormalities suggested an overlap between the NBCC syndrome and Gardner's syndrome, a relationship which has received only brief mention prior to this time. Thus, although the NBCC syndrome and Gardner's syndrome can be clearly differentiated on the basis of multiple basal cell carcinomas in the former and intestinal polyposis in the latter, it would appear that both of these dominantly inherited conditions display considerable overlap in the occurrence of cutaneous cysts, dental abnormalities, fibromas of various organs, and parathyroid abnormalities.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jan 1 1975|