Abstract
Time-lapse imaging of living neurons both in vivo and in vitro has revealed that the growth of axons and dendrites is highly dynamic and characterized by alternating periods of extension and retraction. These growth dynamics are associated with important features of neuronal development and are differentially affected by experimental treatments, but the underlying cellular mechanisms are poorly understood. NeuroRhythmics
Original language | English (US) |
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Pages (from-to) | 147-152 |
Number of pages | 6 |
Journal | Journal of Neuroscience Methods |
Volume | 173 |
Issue number | 1 |
DOIs | |
State | Published - Aug 15 2008 |
Externally published | Yes |
Bibliographical note
Funding Information:The authors wish to thank Ms. Lisa Rising for excellent technical assistance and Gary Banker, Ph.D. for helpful discussions related to quantification of axon behavior. This research was supported by NIAAA R01AA11416 (to TAL). Appendix A
Keywords
- Axonogenesis
- Neuron
- Neuron development
- Process outgrowth
- Time-lapse