Neuropyschological performance in obsessive-compulsive disorder

Kathy J. Christensen, Suck W Kim, Maurice W Dysken, Kathleen Maxwell Hoover

Research output: Contribution to journalArticlepeer-review

225 Scopus citations


Neuropsychological functioning was examined in a group of 18 nondepressed patients with obsessive-compulsive disorder (OCD) and 18 age-, education-, and gender-matched normal controls. A recent nonverbal memory deficit was identified in the patients with OCD. From performance on timed and untimed measures of the same constructs, it appears that OCD patients score more poorly than controls when speed is a factor. Although performance on a timed tactual-spatial motor test was also impaired, it is unclear whether this deficit is attributable to the nonverbal memory and/or speed deficits. Deficits in verbal abilities, including recent verbal memory, were not identified. Results were equivocal for executive function and visual-spatial abilities. The previously established association of recent nonverbal memory abilities with functioning of the right mestal temporal area is discussed in the context of current hypotheses about the neuroanatomic substrate of OCD.

Original languageEnglish (US)
Pages (from-to)4-18
Number of pages15
JournalBiological psychiatry
Issue number1
StatePublished - Jan 1 1992

Bibliographical note

Funding Information:
This research was supported in part by funds from CIBA-GEIGY and the Department of Veterans Affairs. We wish to thank Robert Cudeck, Ph.D., Department of Psychology, University of Minnesota, for statistical consultation.


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