Neuromuscular disorders in the intensive care unit

William A. Marinelli, James W Leatherman

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Neuromuscular disorders encountered in the ICU can be categorized as muscular diseases that lead to ICU admission and those that are acquired in the ICU. This article discusses three neuromuscular disorders can lead to ICU admission and have a putative immune-mediated pathogenesis: the Guillian-Barré syndrome, myasthenia gravis, and dermatomyositis/polymyositis. It also reviews critical care polyneuropathy and ICU acquired myopathy, two disorders that, alone or in combination, are responsible for nearly all cases of severe ICU acquired muscle weakness.

Original languageEnglish (US)
Pages (from-to)915-929
Number of pages15
JournalCritical Care Clinics
Issue number4
StatePublished - Nov 1 2002


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