Neuromuscular Biopsy

Peter I. Karachunski; David Walk

doi:10.1007/978-3-031-70459-8_5

Neuromuscular Biopsy

Peter I. Karachunski, David Walk

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Nerve, muscle, and skin biopsy play important roles in neuromuscular diagnosis. Muscle biopsy can be the most important diagnostic tool in several muscle disorders, including inflammatory myopathies and congenital myopathies, and mitochondrial disorders, where both muscle pathology and genetic testing of muscle cells can be of critical utility. Nerve biopsy is particularly useful to establish a diagnosis in cases of suspected vasculitis or infiltrative conditions. Epidermal nerve fiber density testing from skin biopsy provides a minimally invasive and highly sensitive method to confirm a clinical diagnosis of small fiber neuropathy. In this chapter, we describe the techniques of, and indications for, nerve, muscle, and skin biopsy in neuromuscular disorders.

Original language	English (US)
Title of host publication	Clinical Handbook of Neuromuscular Medicine, Second Edition
Publisher	Springer Nature
Pages	73-85
Number of pages	13
ISBN (Electronic)	9783031704598
ISBN (Print)	9783031704581
DOIs	https://doi.org/10.1007/978-3-031-70459-8_5
State	Published - Jan 1 2025

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2018, 2024.

Keywords

Muscle biopsy
Nerve biopsy
Skin biopsy

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10.1007/978-3-031-70459-8_5

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Neuromuscular Biopsy

Abstract

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