Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo ¹H NMR spectroscopy

Keyphrases

• 1H NMR Spectroscopy 100%
• Striatum 100%
• Huntington's Disease 100%
• Neurochemical Changes 100%
• Metabolic Changes 100%
• Mouse Striatum 100%
• Longitudinal Monitoring 50%
• Disease Progression 50%
• Transgenic 50%
• Oxidative Stress 50%
• Mouse Model 50%
• Homeostasis 50%
• Glutamate 50%
• NMR Spectroscopy 50%
• Neurotransmission 50%
• Glutathione 50%
• Neuronal Integrity 50%
• Treatment Effect 50%
• Disease Treatment 50%
• Glutamine 50%
• Energy Demand 50%
• Neurochemical Profile 50%
• Individual Animal 50%
• Littermate Controls 50%
• N-acetylaspartate 50%
• Littermate 50%
• Myo-inositol 50%
• Quinolinic Acid 50%
• Phosphocreatine 50%
• Gliosis 50%
• Osmotic Stress 50%
• Change in Concentration 50%
• Glycerophosphocholine 50%
• Multiple Processes 50%
• Marker of Disease Progression 50%
• Compensatory Processes 50%
• Membrane Breakdown 50%
• Neuronal Energy 50%
• Metabolite Concentrations 50%

Neuroscience

• In Vivo 100%
• Striatum 100%
• Nuclear Magnetic Resonance Spectroscopy 100%
• Glutamine 33%
• Vitamin C 33%
• Quinolinic Acid 33%
• Glutamic Acid 33%
• Oxidative Stress 33%
• Inositol 33%
• Glutathione 33%
• Creatine Phosphate 33%
• Huntington's Disease 33%
• Glycerophosphorylcholine 33%
• Osmotic Stress 33%
• Synaptic Transmission 33%
• Gliosis 33%