Network-based approaches for the investigation of microbial community structure and function using metagenomics-based data

Research output: Contribution to journalArticlepeer-review

Abstract

Network-based approaches offer a powerful framework to evaluate microbial community organization and function as it relates to a variety of environmental processes. Emerging studies are exploring network theory as a method for data integration that is likely to be critical for the integration of 'omics' data using systems biology approaches. Intricacies of network theory and methodological and computational complexities in network construction, however, impede the use of these tools for translational science. We provide a perspective on the methods of network construction, interpretation and emerging uses for these techniques in understanding host-microbiota interactions.

Original languageEnglish (US)
Pages (from-to)621-631
Number of pages11
JournalFuture Microbiology
Volume17
Issue number8
DOIs
StatePublished - May 2022

Bibliographical note

Publisher Copyright:
© 2022 Future Medicine Ltd.

Keywords

  • Bayesian
  • correlation network
  • metagenomic
  • microbial ecology
  • networks
  • omics

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