NET-Works paediatric obesity prevention trial: 66 month outcomes

Simone A. French; Alicia S. Kunin-Batson; Nancy E. Sherwood; Jerica M. Berge; Ryan Shanley

doi:10.1111/ijpo.13055

NET-Works paediatric obesity prevention trial: 66 month outcomes

Simone A. French, Alicia S. Kunin-Batson, Nancy E. Sherwood, Jerica M. Berge, Ryan Shanley

Research output: Contribution to journal › Article › peer-review

Abstract

Background and Objectives: The NET-Works trial (2012–2018) randomized 534 children ages 2–4 years at baseline and their caregivers to either a 3-year multicomponent obesity prevention intervention or a control group. This research examined treatment effects on body mass index and other outcomes at 66 months. Methods: Parent–child dyads (n = 338) who agreed to participate in a 66 month measurement visit were measured for child BMI, physical activity, diet, and cardiometabolic risk factor variables. Results: At 66 months, no significant treatment effects were observed on BMI (Effect = −0.38; 95% CI = −1.13, 0.37). Subgroup results were consistent with the NET-Works 36 month results. Children with overweight at baseline in the intervention group gained significantly less BMI versus children with overweight in the control group (Effect = −1.28; 95% CI = −2.48, −0.07). Among Hispanic children, those in the intervention gained significantly less BMI than those in the control group (Effect = −1.04; 95% CI = −1.97, −0.11). Conclusions: Evidence suggests that early intervention with children at highest risk for obesity, using community-based, multicomponent, multisetting interventions, may be effective in reducing excess weight gain and obesity among certain subgroups of children. The intervention appeared to be effective in slowing BMI gain 66 months after randomization among children who were already overweight at ages 2–4 years and among children of Hispanic ethnicity.

Original language	English (US)
Article number	e13055
Journal	Pediatric Obesity
Volume	18
Issue number	8
DOIs	https://doi.org/10.1111/ijpo.13055
State	Published - Aug 2023

Bibliographical note

Funding Information:
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin-Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET-Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1-TR002494 and by the Center for Neurobehavioral Development, University of Minnesota.

Funding Information:
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin‐Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET‐Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1‐TR002494 and by the Center for Neurobehavioral Development, University of Minnesota.

Publisher Copyright:
© 2023 The Authors. Pediatric Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.

Keywords

long-term intervention outcomes
paediatric obesity prevention

PubMed: MeSH publication types

Randomized Controlled Trial
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1111/ijpo.13055

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@article{d76920b8ac0747d88b71a8942cb6cf66,

title = "NET-Works paediatric obesity prevention trial: 66 month outcomes",

abstract = "Background and Objectives: The NET-Works trial (2012–2018) randomized 534 children ages 2–4 years at baseline and their caregivers to either a 3-year multicomponent obesity prevention intervention or a control group. This research examined treatment effects on body mass index and other outcomes at 66 months. Methods: Parent–child dyads (n = 338) who agreed to participate in a 66 month measurement visit were measured for child BMI, physical activity, diet, and cardiometabolic risk factor variables. Results: At 66 months, no significant treatment effects were observed on BMI (Effect = −0.38; 95% CI = −1.13, 0.37). Subgroup results were consistent with the NET-Works 36 month results. Children with overweight at baseline in the intervention group gained significantly less BMI versus children with overweight in the control group (Effect = −1.28; 95% CI = −2.48, −0.07). Among Hispanic children, those in the intervention gained significantly less BMI than those in the control group (Effect = −1.04; 95% CI = −1.97, −0.11). Conclusions: Evidence suggests that early intervention with children at highest risk for obesity, using community-based, multicomponent, multisetting interventions, may be effective in reducing excess weight gain and obesity among certain subgroups of children. The intervention appeared to be effective in slowing BMI gain 66 months after randomization among children who were already overweight at ages 2–4 years and among children of Hispanic ethnicity.",

keywords = "long-term intervention outcomes, paediatric obesity prevention",

author = "French, {Simone A.} and Kunin-Batson, {Alicia S.} and Sherwood, {Nancy E.} and Berge, {Jerica M.} and Ryan Shanley",

note = "Funding Information: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin-Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET-Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1-TR002494 and by the Center for Neurobehavioral Development, University of Minnesota. Funding Information: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin‐Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET‐Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1‐TR002494 and by the Center for Neurobehavioral Development, University of Minnesota. Publisher Copyright: {\textcopyright} 2023 The Authors. Pediatric Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.",

year = "2023",

month = aug,

doi = "10.1111/ijpo.13055",

language = "English (US)",

volume = "18",

journal = "Pediatric Obesity",

issn = "2047-6302",

publisher = "Wiley-Blackwell for the International Association for the Study of Obesity",

number = "8",

}

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T1 - NET-Works paediatric obesity prevention trial

T2 - 66 month outcomes

AU - French, Simone A.

AU - Kunin-Batson, Alicia S.

AU - Sherwood, Nancy E.

AU - Berge, Jerica M.

AU - Shanley, Ryan

N1 - Funding Information: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin-Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET-Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1-TR002494 and by the Center for Neurobehavioral Development, University of Minnesota. Funding Information: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung and Blood Institute, the National Institute of Child Health and Human Development, or the National Institutes of Health. Simone A. French conceptualized and designed the study, consulted on the statistical analysis plan, drafted the initial manuscript, and critically reviewed and revised the manuscript. Alicia Kunin‐Batson conceptualized and designed the study, consulted on the statistical analysis plan and critically reviewed the manuscript. Nancy E. Sherwood conceptualized and designed the study and critically reviewed the manuscript. Jerica Berge participated in the design and implementation of the NET‐Works study and critically reviewed the manuscript. Ryan Shanley developed, conducted and interpreted the statistical analysis plan and results, and critically reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was supported by the National Institutes of Health awards R01HD090059 and U01HD068990 and UL1‐TR002494 and by the Center for Neurobehavioral Development, University of Minnesota. Publisher Copyright: © 2023 The Authors. Pediatric Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.

PY - 2023/8

Y1 - 2023/8

N2 - Background and Objectives: The NET-Works trial (2012–2018) randomized 534 children ages 2–4 years at baseline and their caregivers to either a 3-year multicomponent obesity prevention intervention or a control group. This research examined treatment effects on body mass index and other outcomes at 66 months. Methods: Parent–child dyads (n = 338) who agreed to participate in a 66 month measurement visit were measured for child BMI, physical activity, diet, and cardiometabolic risk factor variables. Results: At 66 months, no significant treatment effects were observed on BMI (Effect = −0.38; 95% CI = −1.13, 0.37). Subgroup results were consistent with the NET-Works 36 month results. Children with overweight at baseline in the intervention group gained significantly less BMI versus children with overweight in the control group (Effect = −1.28; 95% CI = −2.48, −0.07). Among Hispanic children, those in the intervention gained significantly less BMI than those in the control group (Effect = −1.04; 95% CI = −1.97, −0.11). Conclusions: Evidence suggests that early intervention with children at highest risk for obesity, using community-based, multicomponent, multisetting interventions, may be effective in reducing excess weight gain and obesity among certain subgroups of children. The intervention appeared to be effective in slowing BMI gain 66 months after randomization among children who were already overweight at ages 2–4 years and among children of Hispanic ethnicity.

AB - Background and Objectives: The NET-Works trial (2012–2018) randomized 534 children ages 2–4 years at baseline and their caregivers to either a 3-year multicomponent obesity prevention intervention or a control group. This research examined treatment effects on body mass index and other outcomes at 66 months. Methods: Parent–child dyads (n = 338) who agreed to participate in a 66 month measurement visit were measured for child BMI, physical activity, diet, and cardiometabolic risk factor variables. Results: At 66 months, no significant treatment effects were observed on BMI (Effect = −0.38; 95% CI = −1.13, 0.37). Subgroup results were consistent with the NET-Works 36 month results. Children with overweight at baseline in the intervention group gained significantly less BMI versus children with overweight in the control group (Effect = −1.28; 95% CI = −2.48, −0.07). Among Hispanic children, those in the intervention gained significantly less BMI than those in the control group (Effect = −1.04; 95% CI = −1.97, −0.11). Conclusions: Evidence suggests that early intervention with children at highest risk for obesity, using community-based, multicomponent, multisetting interventions, may be effective in reducing excess weight gain and obesity among certain subgroups of children. The intervention appeared to be effective in slowing BMI gain 66 months after randomization among children who were already overweight at ages 2–4 years and among children of Hispanic ethnicity.

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KW - paediatric obesity prevention

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ER -

NET-Works paediatric obesity prevention trial: 66 month outcomes

Abstract

Bibliographical note

Keywords

PubMed: MeSH publication types

UN SDGs

Publisher link

Find It

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Cite this