Abstract
Nerve sheath tumors (NSTs) arise from Schwann precursor cells and include neurofibromas, schwannomas, and malignant peripheral NSTs. More recently, hybrid NST with pathological features of both neurofibromas and schwannomas have been described. NSTs can present as sporadic solitary tumors or can present in the setting of neurofibromatosis 1 and 2, and schwannomatosis. This article summarizes the presentation, genetics, imaging, and treatment of these common tumors.
Original language | English (US) |
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Title of host publication | Encyclopedia of the Neurological Sciences |
Publisher | Elsevier Inc. |
Pages | 346-349 |
Number of pages | 4 |
ISBN (Electronic) | 9780123851574 |
ISBN (Print) | 9780123851581 |
DOIs | |
State | Published - Jan 1 2014 |
Externally published | Yes |
Keywords
- Cranial nerve
- Genetics
- Hybrid tumor
- Malignant peripheral nerve sheath tumor
- Nerve sheath tumor
- Neurofibroma
- Neurofibromatosis 1
- Neurofibromatosis 2
- Peripheral nerve
- PET scan
- Ras
- Schwannoma
- Schwannomatosis