Nephrogenic systemic fibrosis and its association with gadolinium exposure during MRI

Naim Issa, Emilio D. Poggio, Richard A. Fatica, Rajiv Patel, Paul M. Ruggieri, Robert J. Heyka

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Nephrogenic systemic fibrosis (NSF) is a newly recognized systemic disorder characterized by widespread tissue fibrosis in patients with impaired renal function. Recent reports suggest that NSF is associated with exposure to gadolinium-based contrast agents used in magnetic resonance imaging. NSF can be very debilitating and can lead to serious complications and death. Health care providers should exercise caution when considering the use of gadolinium-based imaging studies in patients with renal dysfunction.

Original languageEnglish (US)
Pages (from-to)95-111
Number of pages17
JournalCleveland Clinic journal of medicine
Volume75
Issue number2
DOIs
StatePublished - Feb 2008

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    Issa, N., Poggio, E. D., Fatica, R. A., Patel, R., Ruggieri, P. M., & Heyka, R. J. (2008). Nephrogenic systemic fibrosis and its association with gadolinium exposure during MRI. Cleveland Clinic journal of medicine, 75(2), 95-111. https://doi.org/10.3949/ccjm.75.2.95