Neonatal necrotizing enterocolitis an epidemiological study

A Narang, R Rao, O N Bhakoo

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Necrotizing enterocolitis (NEC) was diagnosed in 77 infants among 2200 admissions to the NICU during the period January 1986 to September 1990. The incidence was 0.5% of all live births and 3.5% of NICU admissions. Majority (57.1%) had Stage I of the disease while 23.4% had Stage II and 19.5% had Stage III of the disease. The average birth weight of the babies was 1650 +/- 577 g and gestational age 33.3 +/- 2.6 weeks. Majority (53.2%) were very low birth weight (VLBW) babies. Incidence was significantly more (5.7% vs 0.25%, p < 0.001) in VLBW infants and in preterm infants of gestational age less than 32 weeks (5.2% vs 0.09%, p < 0.001). Multiple risk factors were present in these babies while 8 babies did not have any risk factor. Risk of developing NEC was significantly more if infants had any of these risk factor (p < 0.001). Incidence of severe birth asphyxia was more in Stage I cases (35.7% vs 10.3%, p < 0.05). The age at presentation was 4.9 +/- 4.8 days and majority (96%) presented during the first 14 days. The overall survival was 61% and was 70.5, 77.8 and 13.3% in Stages I, II and III, respectively. VLBW and preterm infants had a higher mortality.

Original languageEnglish (US)
Pages (from-to)1207-14
Number of pages8
JournalIndian pediatrics
Issue number10
StatePublished - Oct 1993


  • Age Factors
  • Apgar Score
  • Asphyxia/complications
  • Birth Weight
  • Enterocolitis, Pseudomembranous/complications
  • Female
  • Gestational Age
  • Hospitals, Pediatric
  • Humans
  • India/epidemiology
  • Infant, Newborn
  • Male
  • Patient Admission
  • Risk Factors
  • Severity of Illness Index
  • Survival Rate

PubMed: MeSH publication types

  • Journal Article


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