Abstract
Heterologous production of natural products in non-native bacteria can be used to increase yields of certain bioactive compounds; however, producing small molecules inside bacteria has numerous limitations. Two reports of the in vitro reconstruction of entire biosynthetic pathways highlight the advantages and challenges of this approach for pathway engineering.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 531-532 |
| Number of pages | 2 |
| Journal | Nature Chemical Biology |
| Volume | 3 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 2007 |