TY - JOUR
T1 - Natural history of conduction abnormalities in a patient with kearns-sayre syndrome
AU - Agrawal, Hitesh
AU - Ekhomu, Omonigho
AU - Choi, Hyoung Won
AU - Naheed, Zahra
PY - 2013/4
Y1 - 2013/4
N2 - Kearns-Sayre syndrome is a rare mitochondrial disorder characterized by large-scale deletion or rearrangement of mitochondrial DNA, which is usually not inherited but occur spontaneously probably at the germ cell level or very early in embryonic development by Mehndiratta, et al. (Neurol India 50:162-167, 2002). Neuromuscular and cardiac conduction abnormalities are most commonly involved in these patients, which may have subtle presenting signs.
AB - Kearns-Sayre syndrome is a rare mitochondrial disorder characterized by large-scale deletion or rearrangement of mitochondrial DNA, which is usually not inherited but occur spontaneously probably at the germ cell level or very early in embryonic development by Mehndiratta, et al. (Neurol India 50:162-167, 2002). Neuromuscular and cardiac conduction abnormalities are most commonly involved in these patients, which may have subtle presenting signs.
KW - Complete heart block
KW - Conduction abnormalities
KW - Kearns-Sayre syndrome
KW - Mitochondrial disorder
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U2 - 10.1007/s00246-012-0365-x
DO - 10.1007/s00246-012-0365-x
M3 - Article
C2 - 22614904
AN - SCOPUS:84879505948
SN - 0172-0643
VL - 34
SP - 1044
EP - 1047
JO - Pediatric Cardiology
JF - Pediatric Cardiology
IS - 4
ER -