Nanobiocatalysis and its potential applications

Jungbae Kim, Jay W. Grate, Ping Wang

Research output: Contribution to journalReview articlepeer-review

398 Scopus citations


Nanobiocatalysis, in which enzymes are incorporated into nanostructured materials, has emerged as a rapidly growing area. Nanostructures, including nanoporous media, nanofibers, carbon nanotubes and nanoparticles, have manifested great efficiency in the manipulation of the nanoscale environment of the enzyme and thus promise exciting advances in many areas of enzyme technology. This review will describe these recent developments in nanobiocatalysis and their potential applications in various fields, such as trypsin digestion in proteomic analysis, antifouling, and biofuel cells.

Original languageEnglish (US)
Pages (from-to)639-646
Number of pages8
JournalTrends in biotechnology
Issue number11
StatePublished - Nov 2008
Externally publishedYes

Bibliographical note

Funding Information:
Parts of this work were supported by a Korea Research Foundation Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund) [KRF-2007–313-D00152]. We appreciate S-H. Jun and B. Lee for their help in the preparation of figures. J.W.G. acknowledges the William R. Wiley Environmental Molecular Sciences Laboratory, a US Department of Energy (DOE) scientific user facility operated for the DOE by the Pacific Northwest National Laboratory (PNNL). The PNNL is a multiprogram national laboratory operated for the US DOE by the Battelle Memorial Institute.


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