Naltrexone: A short-term treatment for opiate dependence

Robert A. Greenstein, Charles P. O'Brien, A. Thomas Mclellan, George E. Woody, John Grabowski, Melody Long, Geraldine Coyle-Perkins, Anita Vittor

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The narcotic antagonist, naltrexone, was studied in 242 patients during a 6-year period. Although a large number of subjects discontinued naltrexone abruptly, treatment was related to a significant decrease in opiate and nonopiate drug use. Methods for improving retention during induction and maintenance are discussed and posttreatment outcome results are presented. The authors conclude that naltrexone may be a useful short-term treatment option for opiate dependence.

Original languageEnglish (US)
Pages (from-to)291-300
Number of pages10
JournalAmerican Journal of Drug and Alcohol Abuse
Volume8
Issue number3
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

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Opioid-Related Disorders
Naltrexone
Opiate Alkaloids
Narcotic Antagonists
Therapeutics
Maintenance
Pharmaceutical Preparations

Cite this

Greenstein, R. A., O'Brien, C. P., Mclellan, A. T., Woody, G. E., Grabowski, J., Long, M., ... Vittor, A. (1981). Naltrexone: A short-term treatment for opiate dependence. American Journal of Drug and Alcohol Abuse, 8(3), 291-300. https://doi.org/10.3109/00952998109009554

Naltrexone : A short-term treatment for opiate dependence. / Greenstein, Robert A.; O'Brien, Charles P.; Mclellan, A. Thomas; Woody, George E.; Grabowski, John; Long, Melody; Coyle-Perkins, Geraldine; Vittor, Anita.

In: American Journal of Drug and Alcohol Abuse, Vol. 8, No. 3, 01.01.1981, p. 291-300.

Research output: Contribution to journalArticle

Greenstein, RA, O'Brien, CP, Mclellan, AT, Woody, GE, Grabowski, J, Long, M, Coyle-Perkins, G & Vittor, A 1981, 'Naltrexone: A short-term treatment for opiate dependence', American Journal of Drug and Alcohol Abuse, vol. 8, no. 3, pp. 291-300. https://doi.org/10.3109/00952998109009554
Greenstein, Robert A. ; O'Brien, Charles P. ; Mclellan, A. Thomas ; Woody, George E. ; Grabowski, John ; Long, Melody ; Coyle-Perkins, Geraldine ; Vittor, Anita. / Naltrexone : A short-term treatment for opiate dependence. In: American Journal of Drug and Alcohol Abuse. 1981 ; Vol. 8, No. 3. pp. 291-300.
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