Naltrexone: A short-term treatment for opiate dependence

Robert A. Greenstein; Charles P. O'Brien; A. Thomas Mclellan; George E. Woody; John Grabowski; Melody Long; Geraldine Coyle-Perkins; Anita Vittor

doi:10.3109/00952998109009554

Naltrexone: A short-term treatment for opiate dependence

Robert A. Greenstein, Charles P. O'Brien, A. Thomas Mclellan, George E. Woody, John Grabowski, Melody Long, Geraldine Coyle-Perkins, Anita Vittor

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The narcotic antagonist, naltrexone, was studied in 242 patients during a 6-year period. Although a large number of subjects discontinued naltrexone abruptly, treatment was related to a significant decrease in opiate and nonopiate drug use. Methods for improving retention during induction and maintenance are discussed and posttreatment outcome results are presented. The authors conclude that naltrexone may be a useful short-term treatment option for opiate dependence.

Original language	English (US)
Pages (from-to)	291-300
Number of pages	10
Journal	American Journal of Drug and Alcohol Abuse
Volume	8
Issue number	3
DOIs	https://doi.org/10.3109/00952998109009554
State	Published - 1981

Bibliographical note

Funding Information:
This investigation was supported in part by NIDA grants 1586 and 01218. The authors would like to thank Ruth Williams, Pete Andrews, Dennis Sacks, Eddie Smith, Doris Battle, and the staff of the DDTS and Inpatient Unit for their assistance. Statistical analyses were performed by Dr McLellan and Anita Vittor.

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title = "Naltrexone: A short-term treatment for opiate dependence",

abstract = "The narcotic antagonist, naltrexone, was studied in 242 patients during a 6-year period. Although a large number of subjects discontinued naltrexone abruptly, treatment was related to a significant decrease in opiate and nonopiate drug use. Methods for improving retention during induction and maintenance are discussed and posttreatment outcome results are presented. The authors conclude that naltrexone may be a useful short-term treatment option for opiate dependence.",

author = "Greenstein, {Robert A.} and O'Brien, {Charles P.} and Mclellan, {A. Thomas} and Woody, {George E.} and John Grabowski and Melody Long and Geraldine Coyle-Perkins and Anita Vittor",

note = "Funding Information: This investigation was supported in part by NIDA grants 1586 and 01218. The authors would like to thank Ruth Williams, Pete Andrews, Dennis Sacks, Eddie Smith, Doris Battle, and the staff of the DDTS and Inpatient Unit for their assistance. Statistical analyses were performed by Dr McLellan and Anita Vittor.",

year = "1981",

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language = "English (US)",

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T2 - A short-term treatment for opiate dependence

AU - Greenstein, Robert A.

AU - O'Brien, Charles P.

AU - Mclellan, A. Thomas

AU - Woody, George E.

AU - Grabowski, John

AU - Long, Melody

AU - Coyle-Perkins, Geraldine

AU - Vittor, Anita

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PY - 1981

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