Abstract
This study reports the development of a rapid visualization method for DNA amplicons. Oligonucleotide-coated gold nanoparticles hierarchically assemble on DNA networks to form globular nanostructures, which precipitate into a distinct visible red pellet. This aims to overcome challenges associated with nanoparticle aggregation and dye-based colorimetric detection in LAMP assays.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4640-4644 |
| Number of pages | 5 |
| Journal | Analytical Methods |
| Volume | 15 |
| Issue number | 36 |
| DOIs | |
| State | Published - Aug 3 2023 |
Bibliographical note
Publisher Copyright:© 2023 The Royal Society of Chemistry.
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