N400 responses of children with primary language disorder: Intervention effects

Mihai Popescu, Marc E. Fey, Jeffrey D. Lewine, Lizbeth H. Finestack, Elena Anda Popescu

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Event-related brain potentials were examined in 6 to 8-year-old children with primary language disorder before and after a 5-week narrative-based language intervention. Participants listened to sentences ending with semantically congruous or incongruous words. By comparison with typical controls, the children with primary language disorder exhibited no pretreatment differences in their N400 responses to congruous and incongruous sentence-final words. After intervention, the typical incongruous-congruous difference was observable owing to a dramatic reduction in the amplitude of the N400 response to congruous words. These characteristic changes in brain responses may reflect a positive effect of the language intervention on the lexical - semantic processing skills in children with language impairment.

Original languageEnglish (US)
Pages (from-to)1104-1108
Number of pages5
JournalNeuroreport
Volume20
Issue number12
DOIs
StatePublished - Aug 5 2009

Keywords

  • Event-related potentials
  • N400
  • Primary language disorder

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