Myosin-driven intracellular transport

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The delivery of intracellular material within cells is crucial for maintaining normal function. Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein particles (RNPs), in plants, fungi, and metazoa. The properties of a given myosin transporter are adapted to move on different actin filament tracks, either on the disordered actin networks at the cell cortex or along highly organized actin bundles to distribute their cargo in a localized manner or move it across long distances in the cell. Transport is controlled by selective recruitment of the myosin to its cargo that also plays a role in activation of the motor.

Original languageEnglish (US)
Article numbera021972
JournalCold Spring Harbor Perspectives in Biology
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2018

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Myosins
Actins
Fungi
Actin Cytoskeleton
Chemical activation
Proteins

Cite this

Myosin-driven intracellular transport. / Titus, Margaret A.

In: Cold Spring Harbor Perspectives in Biology, Vol. 10, No. 3, a021972, 01.03.2018.

Research output: Contribution to journalArticle

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