Myeloid sarcoma: an unusual presentation for acute tracheal stenosis

Eitan Podgaetz, Mark Kriegsmann, Erhan H. Dincer, James S. Allan

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background and Aims: Extramedullary involvement of acute myelogenous leukemia (AML) is rare and has been reported under the terms myeloid sarcoma (MS), granulocytic sarcoma, chloroma, extramedullary acute myeloid leukemia, myeloblastoma and myelosarcoma. The most common extramedullary involvement includes soft tissues and lymph nodes, but it may arise in different sites of the body. There are only very few reports about MS in the pulmonary system, and involvement of the trachea is extremely rare. Methods: This is the first report of initial presentation of MS by severe acute tracheal stenosis. Results: After failed tracheal dilatation, a tracheostomy was performed where tracheal tissue was submitted for pathology. Histology of the tracheal biopsy and bone marrow revealed AML. The patient was subsequently referred to our oncology service for further management. Conclusion: Myeloid sarcoma should be part of the differential for acute tracheal stenosis.

Original languageEnglish (US)
Pages (from-to)800-804
Number of pages5
JournalClinical Respiratory Journal
Volume10
Issue number6
DOIs
StatePublished - Nov 1 2016

Bibliographical note

Publisher Copyright:
© 2015 John Wiley & Sons Ltd

Keywords

  • AML
  • airway obstruction
  • chloroma
  • ganulocytic sarcoma
  • myeloid sarcoma
  • tracheal stenosis

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