Myelin oligodendrocyte glycoprotein antibody-positive optic neuritis with considerable white blood cell elevation in cerebrospinal fluid

Corey J. Miller, Jeffrey Bennett, Michael Lee

Research output: Contribution to journalLetterpeer-review

Abstract

We present a case with an atypical presentation of myelin oligodendrocyte glycoprotein associated disease (MOGAD) presenting with optic neuritis, short-segment transverse myelitis, and significant lymphocytic pleocytosis. The degree of lymphocytic pleocytosis in this case was unusually high and prompted extensive workup. Broad infectious and neoplastic work-up was unremarkable and raised the concern for aseptic meningitis. A literature review was performed of similar cases with documented CSF labs (see Table 1), which demonstrates the unique and significant pleocytosis noted in this case.

Original languageEnglish (US)
Article number102455
JournalMultiple Sclerosis and Related Disorders
Volume46
DOIs
StatePublished - Nov 2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.

Keywords

  • Aseptic meningitis
  • MOG
  • Myelin oligodendrocyte glycoprotein
  • Optic neuritis
  • Pleocytosis

PubMed: MeSH publication types

  • Case Reports
  • Letter
  • Review

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