Mycobacterial infection after liver transplantation: A report of three cases and review of the literature

M. Sterneck, L. Ferrell, N. Ascher, J. Roberts, J. R. Lake

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

We report 3 cases of tuberculosis occurring after liver transplantation. Two patients presented with fever, 2 and 8 months after transplantation, while the third patient was asymptomatic. In the first case, disseminated disease developed rapidly; the other 2 patients presented with pulmonary disease only. In all patients the mycobacterial infection was treated with INH, rifampin and pyrazinamide, as well as ethambutol in the first case. Anti-tuberculous treatment was complicated in the first case by development of severe INH hepatitis after 9 months, necessitating drug withdrawal. The prophylaxis, diagnosis and treatment of mycobacterial infections in liver transplant recipients are discussed.

Original languageEnglish (US)
Pages (from-to)55-61
Number of pages7
JournalClinical Transplantation
Volume6
Issue number1
StatePublished - Jan 1 1992

Keywords

  • Isoniazid
  • Liver transplantation
  • Mycobacterial infection
  • Rifampin

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