Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

Keyphrases

• Human Telomerase Reverse Transcriptase (hTERT) 100%
• Aplastic Anemia 100%
• Telomerase 100%
• Telomerase Activity 50%
• Short Telomere 50%
• Haploinsufficiency 33%
• Risk Factors 16%
• Leukocytes 16%
• Genetic Variation 16%
• Telomere Shortening 16%
• Mechanism of Action 16%
• Enzymatic Activity 16%
• Genetic Variants 16%
• Family Members 16%
• Heterozygous mutation 16%
• Control Subjects 16%
• Co-expression 16%
• Telomere Length 16%
• Blood Cells 16%
• Marrow Cells 16%
• Hematological Abnormalities 16%
• Sequence Variation 16%
• Peripheral Blood Leukocytes 16%
• Marrow Failure 16%
• Acquired Aplastic Anemia 16%
• DKC1 16%
• Hematopoietic Failure 16%
• TERT Promoter mutation 16%
• Buccal mucosa Cells 16%
• NHP2 16%
• NOP10 16%
• Amino Acid Variation 16%
• Non-synonymous mutation 16%
• HTERT Gene 16%
• Catalytic Enzymes 16%

Biochemistry, Genetics and Molecular Biology

• Telomerase 100%
• Telomerase Reverse Transcriptase 100%
• Telomere 33%
• Leukocyte 22%
• Haploinsufficiency 22%
• Genetic Divergence 11%
• RNA 11%
• Amino Acids 11%
• Wild Type 11%
• Enzyme 11%
• Genetic Variation 11%
• Telomere Length 11%
• Enzyme Activity 11%
• Telomere Shortening 11%
• Buccal Mucosa 11%