Mutant prevention concentrations of ABT-492, levofloxacin, moxifloxacin, and gatifloxacin against three common respiratory pathogens

Elizabeth D. Hermsen, Laurie B. Hovde, George N. Konstantinides, John C. Rotschafer

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

The purpose of this study was to compare the mutant prevention concentration (MPC) of ABT-492 to those of levofloxacin, moxifloxacin, and gatifloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. The fluoroquinolones had comparable mutation selection windows, which is the ratio of MPC/MIC, for all isolates.

Original languageEnglish (US)
Pages (from-to)1633-1635
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume49
Issue number4
DOIs
StatePublished - Apr 1 2005

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