Muscular strength as an index of response to therapy in childhood dermatomyositis

J. S. Resnick, M. Mammel, M. O. Mundale, F. J. Kottke

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Dermatomyositis, an inflammatory disease of unknown etiology, causes diffuse symmetrical weakness and atrophy, muscular pain and tenderness, induration of muscles, and the tendency to develop contractures. The disease may follow a prolonged course which can best be managed with steroids and regulation of physical activity if there is an objective criterion for determining the extent of clinical involvement. In 6 children with dermatomyositis, quantitative muscular strength was compared with clinical evaluation of the state of the disease, serum enzyme levels, and other laboratory measures of systemic inflammation. Quantitative evaluation of ankle plantar flexor strength by the method of Beasley or handgrip force by the method of Mundale indicated that muscular strength provided a better criterion for the clinical status of the patient than any of the other laboratory tests studied. In dermatomyositis, the inflammation is equally great in distal and proximal muscles when tested quantitatively. These tests, when used together with enzyme levels and clinical evaluation, permit more effective management of dermatomyositis in children.

Original languageEnglish (US)
Pages (from-to)12-19
Number of pages8
JournalArchives of Physical Medicine and Rehabilitation
Volume62
Issue number1
StatePublished - Jan 1 1981

Fingerprint Dive into the research topics of 'Muscular strength as an index of response to therapy in childhood dermatomyositis'. Together they form a unique fingerprint.

Cite this