Muscle atrophy associated with multiple sclerosis: A benign condition or the onset of amyotrophic lateral sclerosis?

Jeffrey A. Allen, Robert Stein, Richard A. Baker, H. Royden Jones

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

When muscular atrophy develops in multiple sclerosis (MS) patients, its etiology may vary from benign to serious. We describe an individual with a 24-year history of MS who developed amyotrophic lateral sclerosis (ALS). The literature is reviewed with particular attention to the clinical and electrophysiologic characteristics of patients with MS and muscular atrophy and to those rare patients with concurrent MS and ALS. Circumstances warranting a heightened suspicion for concurrent ALS are discussed and careful evaluation of similar patients is encouraged.

Original languageEnglish (US)
Pages (from-to)706-708
Number of pages3
JournalJournal of Clinical Neuroscience
Volume15
Issue number6
DOIs
StatePublished - Jun 1 2008

Keywords

  • Amyotrophic lateral sclerosis
  • Benign atrophy
  • Motor neuron disease
  • Multiple sclerosis
  • Muscle atrophy

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