Abstract
Chromosomally integrated human herpesvirus-6 (ciHHV-6) can be transmitted from parent to child or via allogeneic hematopoietic cell transplantation (HCT). We report a case of ciHHV-6 transmitted via syngeneic HCT, and vertically across 3 generations. ciHHV-6 was transmitted from a parent to the patient and her identical twin, and from the patient to her son. The patient underwent syngeneic HCT as rescue from chemotherapy-induced aplasia during which ciHHV-6 was re-transmitted to her, this time from her identical twin. This is the first report, to our knowledge, of a patient acquiring ciHHV-6 once via germline from a parent and again via syngeneic HCT from an identical twin.
Original language | English (US) |
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Article number | e12816 |
Journal | Transplant Infectious Disease |
Volume | 20 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2018 |
Bibliographical note
Publisher Copyright:© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Keywords
- HHV-6
- allogeneic
- chromosomally integrated
- syngeneic
- transplantation