Multiple sclerosis on steroids

Matthew S. Johnson; Michael S. Lee; Brian R. Younge; Valerie Purvin

doi:10.1016/j.survophthal.2009.11.002

Multiple sclerosis on steroids

Matthew S. Johnson, Michael S. Lee, Brian R. Younge, Valerie Purvin

Ophthalmology & Visual Neurosciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

Original language	English (US)
Pages (from-to)	460-466
Number of pages	7
Journal	Survey of Ophthalmology
Volume	55
Issue number	5
DOIs	https://doi.org/10.1016/j.survophthal.2009.11.002
State	Published - Sep 2010

Keywords

Bilateral visual loss
Fulminant
Marburg
Multiple sclerosis
Optic neuritis
Treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1016/j.survophthal.2009.11.002

Find It

Find It at U of M Libraries

Cite this

@article{5175955fecd84d3eb8efd94a7cfcbe56,

title = "Multiple sclerosis on steroids",

abstract = "A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.",

keywords = "Bilateral visual loss, Fulminant, Marburg, Multiple sclerosis, Optic neuritis, Treatment",

author = "Johnson, \{Matthew S.\} and Lee, \{Michael S.\} and Younge, \{Brian R.\} and Valerie Purvin",

year = "2010",

month = sep,

doi = "10.1016/j.survophthal.2009.11.002",

language = "English (US)",

volume = "55",

pages = "460--466",

journal = "Survey of Ophthalmology",

issn = "0039-6257",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Multiple sclerosis on steroids

AU - Johnson, Matthew S.

AU - Lee, Michael S.

AU - Younge, Brian R.

AU - Purvin, Valerie

PY - 2010/9

Y1 - 2010/9

N2 - A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

AB - A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

KW - Bilateral visual loss

KW - Fulminant

KW - Marburg

KW - Multiple sclerosis

KW - Optic neuritis

KW - Treatment

UR - https://www.scopus.com/pages/publications/77955331977

UR - https://www.scopus.com/inward/citedby.url?scp=77955331977&partnerID=8YFLogxK

U2 - 10.1016/j.survophthal.2009.11.002

DO - 10.1016/j.survophthal.2009.11.002

M3 - Article

C2 - 20347108

AN - SCOPUS:77955331977

SN - 0039-6257

VL - 55

SP - 460

EP - 466

JO - Survey of Ophthalmology

JF - Survey of Ophthalmology

IS - 5

ER -

Multiple sclerosis on steroids

Abstract

Keywords

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this