Multimodal functional and still imaging of a transplanted human heart reanimated using Visible Heart® methodologies

Michael G. Bateman, Tinen L. Iles, Stephen G. Quallich, Andrew W. Shaffer, Paul A. Iaizzo

Research output: Contribution to journalArticlepeer-review


Background: Our research team obtained a human heart with the right lung attached from a recent transplantation patient via a research collaboration with LifeSource, a local organ procurement organization. The heart and lungs were not viable for transplant given the patient's medical history and were subsequently offered to the University of Minnesota for research purposes. Methods: Using Visible Heart® methodologies, we reanimated the specimen en bloc and collected multimodal direct visualization from inside the cardiac chambers and great vessels of the functioning heart. Results: Video footage, using videoscopic and fluoroscopic imaging, was captured and is presented in this report as supporting material. Multiple still images highlight the surgical suture sites of the transplantation procedures. Conclusions: This multimodal imaging offers unique educational value for medical students, clinicians, and medical device designers for improving transplantation techniques and patient outcomes.

Original languageEnglish (US)
Pages (from-to)668-671
Number of pages4
JournalJournal of Cardiac Surgery
Issue number3
StatePublished - Mar 1 2020

Bibliographical note

Funding Information:
This study would not be possible without the generosity of the organ donor and family, as well as the laboratory's continued collaboration with LifeSource. The authors also thank Monica Mahre for assisting with manuscript preparation and submission. This study was funded, in part, by a research contract with Medtronic, PLC.

Publisher Copyright:
© 2020 Wiley Periodicals, Inc.


  • cardiac
  • ex-vivo
  • reanimation
  • transplant


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