TY - CHAP
T1 - Multilocus sequence typing and pulsed field gel electrophoresis of otitis media causing pathogens
AU - Thomas, Jonathan C.
AU - Pettigrew, Melinda M.
PY - 2009
Y1 - 2009
N2 - Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis are the three leading bacteria species associated with otitis media. Defining the molecular epidemiology of bacteria known to cause otitis media is of great importance, in both clinical and research settings. PFGE and MLST provide data for the characterization of isolates' genetic relatedness, yet they differ in the types of studies for which they are most useful. Consequently, knowledge of both techniques is important for laboratories intending to study the molecular epidemiology of otitis media-associated bacterial pathogens.
AB - Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis are the three leading bacteria species associated with otitis media. Defining the molecular epidemiology of bacteria known to cause otitis media is of great importance, in both clinical and research settings. PFGE and MLST provide data for the characterization of isolates' genetic relatedness, yet they differ in the types of studies for which they are most useful. Consequently, knowledge of both techniques is important for laboratories intending to study the molecular epidemiology of otitis media-associated bacterial pathogens.
KW - eBURST
KW - Haemophilus influenzae
KW - Molecular epidemiology
KW - Moraxella catarrhalis
KW - Multilocus sequence typing
KW - Otitis media
KW - Pulsed field gel electrophoresis
KW - Streptococcus pneumoniae
UR - http://www.scopus.com/inward/record.url?scp=84934434621&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84934434621&partnerID=8YFLogxK
U2 - 10.1007/978-1-59745-523-7_11
DO - 10.1007/978-1-59745-523-7_11
M3 - Chapter
C2 - 18839348
AN - SCOPUS:84934434621
SN - 9781934115626
T3 - Methods in Molecular Biology
SP - 179
EP - 190
BT - Auditory and Vestibular Research
PB - Humana Press
ER -
