Multi-omics approach profiling metabolic remodeling in early systolic dysfunction and in overt systolic heart failure

Keyphrases

• Omics Approaches 100%
• Systolic Heart Failure 100%
• Systolic Dysfunction 100%
• Metabolic Remodeling 100%
• Sham 60%
• PKA Signaling 40%
• Pathophysiology 20%
• Amino Acids 20%
• Heart Failure 20%
• Signaling Pathway 20%
• Metabolism 20%
• Proteomics Metabolomics 20%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 20%
• Rat Model 20%
• Mitochondrial Proteins 20%
• Signaling Crosstalk 20%
• Biological Samples 20%
• Myocardial Tissue 20%
• Respiration 20%
• Metabolic Pathway 20%
• Cellular Signaling 20%
• Glutamine 20%
• Left Ventricular Strain 20%
• Oxidative Phosphorylation (OXPHOS) 20%
• Myocardial Remodeling 20%
• Branched-chain Amino Acids 20%
• Krebs Cycle 20%
• Glycolytic Metabolism 20%
• Shotgun Proteomics 20%
• Mitochondrial Fatty Acid Oxidation 20%
• Untargeted Metabolomics 20%
• Tryptophan Degradation 20%
• Glycogen Breakdown 20%
• Pyruvate Metabolism 20%
• Glucose Degradation 20%
• Tandem Mass Tag 20%
• AMPK Signaling 20%

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Tamsulosin 100%
• Signal Transduction 66%
• Amino Acids 66%
• Mitochondrial Protein 33%
• Rat Model 33%
• Beta Oxidation 33%
• Glutamine 33%
• Citric Acid Cycle 33%
• Proteomics 33%
• Metabolomics 33%
• Krebs Cycle 33%
• Oxidative Phosphorylation 33%
• Shotgun Proteomics 33%
• Tandem Mass Tag 33%
• AMPK Signaling 33%
• AMP-activated Protein Kinase 33%
• Tryptophan 33%