MRI vs. histologic measurement of breast cancer following chemotherapy: Comparison with x-ray mammography and palpation

P. T. Weatherall, Gregory F. Evans, Gregory J. Metzger, M. Hossein Saborrian, A. Marilyn Leitch

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140 Scopus citations

Abstract

Twenty consecutive patients with breast cancer were evaluated following chemotherapy using MRI to assess the size of cancer residua and compare these data with subsequent histologic measurements of the viable tumor. This retrospective study also involved assessment of the preoperative size of the malignancy as determined by physical exam and x-ray mammogram. These values were later compared with the histology. The tumor size correlation coefficient between MRI and pathologic analysis was the highest, at 0.93. Physical exam and x-ray mammography (available for 17 patients) produced correlation coefficients of 0.72 and 0.63, respectively, compared to histologic measurement. The accuracy of MRI did not vary with the size of cancer residua. MRI is an accurate method for preoperative assessment of breast cancer residua following chemotherapy.

Original languageEnglish (US)
Pages (from-to)868-875
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume13
Issue number6
DOIs
StatePublished - Jun 1 2001

Keywords

  • Breast neoplasms
  • Comparative studies
  • Malignant neoplasm
  • MR
  • Staging

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