Motor Neuron Disorders

David Walk; Melissa Cook

doi:10.1007/978-3-031-70459-8_9

Motor Neuron Disorders

David Walk, Melissa Cook

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Disorders of motor neurons include amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), spinobulbar muscular atrophy (SBMA, or Kennedy’s disease), spinal muscular atrophy (SMA), poliomyelitis, and monomelic amyotrophy (Hirayama disease). Although the pathology, genetics, and clinical features of ALS are well-established, neither a unifying etiology nor a highly effective treatment have been identified. Because of this, as well as its inexorable progression and numerous clinical manifestations, the management of ALS currently requires multidisciplinary care. People living with ALS, PLS and SBMA have overlapping needs and are commonly cared for in the same multidisciplinary setting. The differential diagnosis of ALS, including conditions that can mimic ALS, are discussed as well.

Original language	English (US)
Title of host publication	Clinical Handbook of Neuromuscular Medicine, Second Edition
Publisher	Springer Nature
Pages	173-192
Number of pages	20
ISBN (Electronic)	9783031704598
ISBN (Print)	9783031704581
DOIs	https://doi.org/10.1007/978-3-031-70459-8_9
State	Published - Jan 1 2025

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Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2018, 2024.

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Motor Neuron Disorders

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