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Morphine inhibits VEGF expression in myocardial ischemia
S. Roy
, S. Balasubramanian
, Jinghua Wang
, Y. Chandrashekhar
, R. Charboneau
, Roderick Barke
Surgery
Medicine - Veteran's Administration Medical Center
Research output
:
Contribution to journal
›
Article
›
peer-review
37
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Scopus citations
Overview
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Keyphrases
Myocardial Ischemia
100%
Morphine
100%
Hypoxia-inducible factor-1α (HIF-1α)
100%
Vascular Endothelial Growth Factor Expression
100%
Vascular Endothelial Growth Factor
83%
Immunoblot
66%
Protein Expression
50%
Hypoxia
50%
Kinase Activity
50%
Mitogen-activated Protein Kinase
50%
Phospho-Akt
50%
Phosphoinositide 3-kinase (PI3K)
33%
Immunohistochemistry
33%
Myocytes
33%
Coronary Ligation
33%
Electromobility Shift Assays
33%
Protein Binding
16%
Quantitative PCR
16%
Protein Concentration
16%
Nuclear Proteins
16%
MRNA Expression
16%
Opioid Receptors
16%
Signal Transduction Pathway
16%
Enzyme-linked Immunosorbent Assay (ELISA)
16%
Morphine Treatment
16%
Infarct Size
16%
Western Immunoblotting
16%
ERK1
16%
Receptor Mechanisms
16%
VEGF165
16%
VEGF121
16%
Protein Estimation
16%
In Vivo Rat
16%
Collateral Circulation
16%
Akt Kinase Activity
16%
DNA Response Element
16%
Morphine Analgesia
16%
In Vitro Primary Cultures
16%
Medicine and Dentistry
Heart Muscle Ischemia
100%
Hypoxia
100%
Vasculotropin
100%
Morphine
100%
Fibrinogen
66%
Immunoblotting
55%
Protein Expression
33%
Mitogen Activated Protein Kinase 1
33%
Protein Kinase B
33%
In Vitro
22%
Immunohistochemistry
22%
Phosphoinositide 3-Kinase
22%
Coronary Artery Ligation
22%
Cardiac Muscle Cell
22%
Messenger RNA
22%
Quantitative Reverse Transcription Polymerase Chain Reaction
11%
Analgesia
11%
Infarction
11%
Primary Culture
11%
Enzyme Linked Immunosorbent Assay
11%
Mitogen Activated Protein Kinase 3
11%
Collateral Circulation
11%
DNA Responsive Element
11%
Protein Binding
11%
Transduction Mechanism
11%
Receptor Mechanism
11%
Nuclear Protein
11%
Signal Transduction
11%
Opioid Receptor
11%
Pharmacology, Toxicology and Pharmaceutical Science
Heart Muscle Ischemia
100%
Hypoxia
100%
Vasculotropin
100%
Morphine
100%
Fibrinogen
66%
Western Blot
55%
Rat
44%
Mitogen Activated Protein Kinase 1
33%
Protein Kinase B
33%
Phosphatidylinositol 3 Kinase
22%
Messenger RNA
22%
Protein Binding
11%
Enzyme-Linked Immunosorbent Assay
11%
Primary Culture
11%
Opiate Receptor
11%
Infarction
11%
Mitogen Activated Protein Kinase 3
11%
Nuclear Protein
11%
Reverse Transcriptase
11%
Immunology and Microbiology
Vasculotropin
100%
Fibrinogen
85%
Kinase
85%
Phosphotransferase
85%
Western Blot
71%
Rat
57%
Protein Expression
42%
Cardiac Muscle Cell
28%
In Vitro
28%
Quantitative Reverse Transcription Polymerase Chain Reaction
14%
Enzyme-Linked Immunosorbent Assay
14%
Primary Culture
14%
DNA Responsive Element
14%
Signal Transduction
14%
Protein Binding
14%
Collateral Circulation
14%