More on the need for circadian, circaseptan and circannual optimization of cyclosporine therapy

T. Liu; M. Cavallini; F. Halberg; Germaine G Cornelissen-Guillaume; J. Field; D. E.R. Sutherland

doi:10.1007/BF01975877

More on the need for circadian, circaseptan and circannual optimization of cyclosporine therapy

T. Liu, M. Cavallini, F. Halberg, Germaine G Cornelissen-Guillaume, J. Field, D. E.R. Sutherland

Physiology

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Cyclosporine chronotherapy of pancreas-allotransplanted rats revealed, beyond a circadian stage-dependence of equal daily doses, further gain in graft function from doses varying from day to day with an about 7-day periodicity, the first highest dose being given on the 3rd or 5th day after surgery.

Original language	English (US)
Pages (from-to)	20-22
Number of pages	3
Journal	Experientia
Volume	42
Issue number	1
DOIs	https://doi.org/10.1007/BF01975877
State	Published - Jan 1986

Keywords

Pancreatic allograft
circadian
circannual
circaseptan
cyclosporine chronotherapy

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10.1007/BF01975877

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abstract = "Cyclosporine chronotherapy of pancreas-allotransplanted rats revealed, beyond a circadian stage-dependence of equal daily doses, further gain in graft function from doses varying from day to day with an about 7-day periodicity, the first highest dose being given on the 3rd or 5th day after surgery.",

keywords = "Pancreatic allograft, circadian, circannual, circaseptan, cyclosporine chronotherapy",

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AU - Halberg, F.

AU - Cornelissen-Guillaume, Germaine G

AU - Field, J.

AU - Sutherland, D. E.R.

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N2 - Cyclosporine chronotherapy of pancreas-allotransplanted rats revealed, beyond a circadian stage-dependence of equal daily doses, further gain in graft function from doses varying from day to day with an about 7-day periodicity, the first highest dose being given on the 3rd or 5th day after surgery.

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KW - Pancreatic allograft

KW - circadian

KW - circannual

KW - circaseptan

KW - cyclosporine chronotherapy

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More on the need for circadian, circaseptan and circannual optimization of cyclosporine therapy

Abstract

Keywords

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