Monounsaturated fatty acids, olive oil and blood pressure: Epidemiological, clinical and experimental evidence

Álvaro Alonso, Valentina Ruiz-Gutierrez, Miguel Ángel Martínez-González

Research output: Contribution to journalReview articlepeer-review

102 Scopus citations


Diet has an important role in the prevention and treatment of hypertension. In early epidemiological studies, conducted mainly in the USA, monounsaturated fatty acids showed a deleterious association with blood pressure or no relationship at all. However, more recent studies, conducted in Mediterranean countries, have shed new light on this issue. In the present review we summarise the main results of epidemiological studies and feeding trials, and explain the possible mechanisms through which monounsaturated fatty acids, and specifically olive oil as the major dietary source of this type of fat in Mediterranean countries, could exert a favourable effect on blood pressure.

Original languageEnglish (US)
Pages (from-to)251-257
Number of pages7
JournalPublic health nutrition
Issue number2
StatePublished - Apr 2006
Externally publishedYes

Bibliographical note

Funding Information:
This work was partially funded by the Spanish Ministry of Health (Fondo de Investigaciones Sanitarias, project G03/140, Red Tematica de Dieta y Enfermedad Cardiovascular). A.A. was partially supported by a Fulbright fellowship and by an MMA Foundation for Medical Research grant. We are grateful to our dietitian, Ms Carmen de la Fuente, for her nutritional advice in the preparation of the manuscript. There is no conflict of interest. This study has not received any funding from the olive oil industry.


  • Hypertension
  • Mediterranean diet
  • Monounsaturated fatty acids
  • Olive oil


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