Monodisperse gas-filled microparticles from reactions in double emulsions

Wynter J. Duncanson, Alireza Abbaspourrad, Ho Cheung Shum, Shin Hyun Kim, Laura L.A. Adams, David A. Weitz

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


We present a strategy for preparing size-controlled gas-filled microparticles using two aqueous components that chemically react to produce the gas. We use a dual-bore microfluidic device to isolate the reactants of two gas-producing reactions until they are encapsulated in the outer droplet. The reactants in the monodisperse droplets merge and produce the gas bubbles, which are stabilized with a surfactant and form the core of the microparticles. The number and size of the generated gas bubbles are governed by the gas-forming reaction used. Our versatile strategy can be applied to a wide range of gas-producing reactions.

Original languageEnglish (US)
Pages (from-to)6742-6745
Number of pages4
Issue number17
StatePublished - May 1 2012
Externally publishedYes


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