Molecular responses of fishes to elevated carbon dioxide

Clark E. Dennis, Daniel F. Kates, Matthew R. Noatch, Cory D. Suski

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Hypercarbia, or elevated carbon dioxide, is an environmental challenge that can have detrimental effects on the physiology and performance of aquatic organisms. With aquatic hypercarbia predicted to become more prevalent in the future due to global climate change, it is important to quantify how hypercarbia impacts aquatic organisms, especially fish. The impact of hypercarbia on the behavior and physiology of fishes has been well studied, but relatively few studies have examined the molecular processes that underlie resulting behavioral and physiological changes. In an effort to define the molecular response of fishes to acute hypercarbia exposure, bluegill (Lepomis macrochirus) and silver carp (Hypophthalmichthys molitrix) were exposed to either 30mgL<sup>-1</sup> CO<inf>2</inf> (pCO<inf>2</inf>≈15,700μatm) or ambient (10mgL<sup>-1</sup> CO<inf>2</inf>; pCO<inf>2</inf>≈ 920 μatm) conditions for 1h and the expression of a variety of genes, across three tissues, were compared. Exposure to 30mgL<sup>-1</sup> CO<inf>2</inf> in bluegill and silver carp resulted in an increase in c-fos, hif1-α, and gr-2 transcripts, while silver carp alone showed increases in hsp70 and hsc70-2 mRNA. This study demonstrates that acute hypercarbia exposure impacts gene expression in a species and tissue specific manner, which can be useful in identifying potential mechanisms for hypercarbia tolerance between species, and pinpoint specific tissues that are sensitive to hypercarbia exposure.

Original languageEnglish (US)
Pages (from-to)224-231
Number of pages8
JournalComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Volume187
DOIs
StatePublished - Sep 1 2015

Keywords

  • Erythrocytes
  • Fish
  • Genes
  • Gill
  • Hypercarbia
  • Stress
  • Tolerance

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

Fingerprint

Dive into the research topics of 'Molecular responses of fishes to elevated carbon dioxide'. Together they form a unique fingerprint.

Cite this