TY - GEN
T1 - Molecular packing of carbohydrate oligomer encapsulants - a free volume perspective
AU - Roussenova, M.
AU - Townrow, S.
AU - Murith, M.
AU - Ubbink, J.
AU - Alam, A.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - Positron annihilation lifetime spectroscopy (PALS) is used in conjunction with dilatome-try to analyse the effects of water and low molecular weight diluents (maltose and glycerol) on the molecular organisation and density of carbohydrate oligomers commonly used in the pharmaceutical and food industries for the formulation of encapsulation matrices. In the glassy state, both maltose and glycerol act as packing enhancers, causing a non-linear decrease in the average molecular hole size of the carbohydrate matrices. Water exists in a highly non-ideal state in these systems and it alters the molecular organisation of the matrices in a complex manner, whereby it can act either as an anti-plasticiser or a plasticiser, depending on the level of hydration.
AB - Positron annihilation lifetime spectroscopy (PALS) is used in conjunction with dilatome-try to analyse the effects of water and low molecular weight diluents (maltose and glycerol) on the molecular organisation and density of carbohydrate oligomers commonly used in the pharmaceutical and food industries for the formulation of encapsulation matrices. In the glassy state, both maltose and glycerol act as packing enhancers, causing a non-linear decrease in the average molecular hole size of the carbohydrate matrices. Water exists in a highly non-ideal state in these systems and it alters the molecular organisation of the matrices in a complex manner, whereby it can act either as an anti-plasticiser or a plasticiser, depending on the level of hydration.
KW - Anti-plasticisation
KW - Molecular packing
KW - Plasticisation
KW - Positron annihilation
UR - http://www.scopus.com/inward/record.url?scp=84871079438&partnerID=8YFLogxK
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U2 - 10.4028/www.scientific.net/MSF.733.96
DO - 10.4028/www.scientific.net/MSF.733.96
M3 - Conference contribution
AN - SCOPUS:84871079438
SN - 9783037855188
T3 - Materials Science Forum
SP - 96
EP - 99
BT - Positron and Positronium Chemistry X
PB - Trans Tech Publications Ltd
T2 - 10th International Workshop on Positron and Positronium Chemistry, PPC-10
Y2 - 5 September 2011 through 9 September 2011
ER -