Abstract
The molecular mechanisms of tolerance and dependence appear to be extremely complex. A unitary mechanism to explain both processes has not been found and some investigations have indicated that separate mechanisms are in fact involved. The neuroblastoma x glioma NG108-15 hybrid cells provide a relatively simple model system with which these complex mechanisms may be elucidated. Only until some understanding is mastered on this single cell level, will more intricate brain systems be comprehensible.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-128 |
| Number of pages | 12 |
| Journal | NIDA Research Monograph Series |
| Volume | NO. 62 |
| State | Published - 1985 |
| Externally published | Yes |