Abstract
The molecular mechanisms of tolerance and dependence appear to be extremely complex. A unitary mechanism to explain both processes has not been found and some investigations have indicated that separate mechanisms are in fact involved. The neuroblastoma x glioma NG108-15 hybrid cells provide a relatively simple model system with which these complex mechanisms may be elucidated. Only until some understanding is mastered on this single cell level, will more intricate brain systems be comprehensible.
Original language | English (US) |
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Pages (from-to) | 117-128 |
Number of pages | 12 |
Journal | NIDA Research Monograph Series |
Volume | NO. 62 |
State | Published - 1985 |
Externally published | Yes |