TY - JOUR
T1 - Molecular epidemiology of PRRSV
T2 - A phylogenetic perspective
AU - Shi, Mang
AU - Lam, Tommy Tsan Yuk
AU - Hon, Chung Chau
AU - Hui, Raymond Kin Hei
AU - Faaberg, Kay S.
AU - Wennblom, Trevor
AU - Murtaugh, Michael P.
AU - Stadejek, Tomasz
AU - Leung, Frederick Chi Ching
PY - 2010/12
Y1 - 2010/12
N2 - Since its first discovery two decades ago, porcine reproductive and respiratory syndrome virus (PRRSV) has been the subject of intensive research due to its huge impact on the worldwide swine industry. Thanks to the phylogenetic analyses, much has been learned concerning the genetic diversity and evolution history of the virus. In this review, we focused on the evolutionary and epidemiological aspects of PRRSV from a phylogenetic perspective. We first described the diversity and transmission dynamics of Type 1 and 2 PRRSV, respectively. Then, we focused on the more ancient evolutionary history of PRRSV: the time of onset of all existing PRRSV and an origin hypothesis were discussed. Finally, we summarized the results from previous recombination studies to assess the potential impact of recombination on the virus epidemiology.
AB - Since its first discovery two decades ago, porcine reproductive and respiratory syndrome virus (PRRSV) has been the subject of intensive research due to its huge impact on the worldwide swine industry. Thanks to the phylogenetic analyses, much has been learned concerning the genetic diversity and evolution history of the virus. In this review, we focused on the evolutionary and epidemiological aspects of PRRSV from a phylogenetic perspective. We first described the diversity and transmission dynamics of Type 1 and 2 PRRSV, respectively. Then, we focused on the more ancient evolutionary history of PRRSV: the time of onset of all existing PRRSV and an origin hypothesis were discussed. Finally, we summarized the results from previous recombination studies to assess the potential impact of recombination on the virus epidemiology.
KW - Evolution
KW - Molecular epidemiology
KW - Phylogenetic analyses
KW - Porcine reproductive and respiratory syndrome virus
UR - http://www.scopus.com/inward/record.url?scp=78649324151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649324151&partnerID=8YFLogxK
U2 - 10.1016/j.virusres.2010.08.014
DO - 10.1016/j.virusres.2010.08.014
M3 - Review article
C2 - 20837072
AN - SCOPUS:78649324151
SN - 0168-1702
VL - 154
SP - 7
EP - 17
JO - Virus research
JF - Virus research
IS - 1-2
ER -