Molecular cloning and sequence analysis of the cDNA for northern pike (Esox lucius) growth hormone.

J. F. Schneider, S. H. Myster, P. B. Hackett, K. S. Guise, A. J. Faras

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The complete nucleotide sequence of the northern pike (Esox lucius) cDNA for pregrowth hormones was determined from clones derived from a pituitary gland cDNA library. Seventeen cDNA clones were isolated from a single mRNA species. A cDNA of 1,227 nucleotides was sequenced and found to encode a polypeptide of 209 amino acid residues, which included a putative signal sequence of 22 amino acid residues. Sequence comparison of the northern pike growth hormone gene to other known growth hormone genes revealed similarities closest to other members of the superorder Protacanthopterygii, which includes the Salmonidae family (i.e., salmon and trout).

Original languageEnglish (US)
Pages (from-to)106-112
Number of pages7
JournalMolecular marine biology and biotechnology
Volume1
Issue number2
StatePublished - Apr 1992

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