Molecular characterization of a cloned dolphin mitochondrial genome

Šárka O. Southern, Peter J. Southern, Andrew E. Dizon

Research output: Contribution to journalArticle

140 Scopus citations

Abstract

DNA clones have been isolated that span the complete mitochondrial (mt) genome of the dolphin, Cephalorhynchus commersonii. Hybridization experiments with purified primate mtDNA probes have established that there is close resemblance in the general organization of the dolphin mt genome and the terrestrial mammalian mt genomes. Sequences covering 2381 bp of the dolphin mt genome from the major noncoding region, three tRNA genes, and parts of the genes encoding cytochrome b, NADH dehydrogenase subunit 3 (ND3), and 16S rRNA have been compared with corresponding regions from other mammalian genomes. There is a general tendency throughout the sequenced regions for greater similarity between dolphin and bovine mt genomes than between dolphin and rodent or human mt genomes.

Original languageEnglish (US)
Pages (from-to)32-42
Number of pages11
JournalJournal of Molecular Evolution
Volume28
Issue number1-2
DOIs
StatePublished - Dec 1 1988

Keywords

  • Conservation of genome organization
  • D-loop sequence
  • Sequence evolution
  • Similarity blocks

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