Molar-incisor-malformation in a paediatric cancer patient: Case report

Athina Tosiou, Andriana Mastrokalou, Hari S. Prasad, Konstantinos I. Tosios, Ioannis G. Koutlas

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To report a case of molar-incisor-malformation (MIM) in a 7-year-old boy with a history of congenital infantile fibrosarcoma of the upper chest, which was surgically treated, without adjuvant radio/chemotherapy. Material and Methods: The boy presented with mobility and pain on percussion of the permanent mandibular first molars. The radiographic features were suggestive of MIM. Both teeth were extracted and processed for conventional light microscopic examination and non-decalcified ground sections. Results: The microscopic features confirmed the diagnosis of MIM. Regular follow-up was recommended. Conclusions: Medical interventions during hospitalization for cancer treatment, other than chemo/radiotherapy, may cause MIM by adversely affecting the function of Hertwig's epithelial root sheath. Regular dental screening in paediatric cancer patients may reveal more MIM cases and help in elucidating its pathogenesis.

Original languageEnglish (US)
Pages (from-to)53-58
Number of pages6
JournalOral Surgery
Volume17
Issue number1
DOIs
StatePublished - Feb 2024

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Oral Surgery published by British Association of Oral Surgeons and John Wiley & Sons Ltd.

Keywords

  • dentin dysplasia
  • molar-incisor-malformation
  • tooth abnormalities

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