Modulation of endogenous opioid signaling by inhibitors of puromycin-sensitive aminopeptidase

Keyphrases

• Opioid Signaling 100%
• Endogenous Opioids 100%
• Puromycin-sensitive Aminopeptidase 100%
• Enkephalin 50%
• Puromycin 37%
• Opioid Receptors 25%
• Local Concentration 12%
• Pain Management 12%
• Sulfur 12%
• Metabolic 12%
• Metabolism 12%
• Molecular Modeling 12%
• Opioid Antagonist 12%
• Analgesic Effect 12%
• Neuropeptides 12%
• Degradative Enzymes 12%
• Naloxone 12%
• Pain Response 12%
• Opioid Peptides 12%
• Antinociception 12%
• Met-enkephalin 12%
• Chemical Classes 12%
• Brain Slice 12%
• Chloro 12%
• Inhibitory Potency 12%
• Structure-activity Relationship Studies 12%
• Local Release 12%
• Rapid Hydrolysis 12%
• Aromatic Amino Acids 12%
• Enhanced Selectivity 12%
• Pharmacokinetic Evaluation 12%
• Endogenous Opioid System 12%
• Plasma Instabilities 12%
• Enkephalinase 12%
• Diphenylmethyl Ethers 12%
• Effective Pain Management 12%
• Innovative Approach 12%
• In Vivo Applications 12%
• Aminopeptidase Inhibitors 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Endorphin 100%
• Aminopeptidase 100%
• Puromycin 100%
• Enkephalin 40%
• Opiate Receptor 30%
• Naloxone 10%
• Opioid Antagonist 10%
• Sulfur 10%
• Structure Activity Relationship 10%
• Pharmacokinetics 10%
• Pain 10%
• Analgesic Agent 10%
• Membrane Metalloendopeptidase 10%
• Neuropeptide 10%
• Lead Compound 10%
• Antinociception 10%
• Metenkephalin 10%
• Opiate Peptide 10%
• Puromycin Aminonucleoside 10%
• Aminopeptidase Inhibitor 10%
• Aromatic Amino Acid 10%